Khabor Wala Desk
Published: 6th October 2025, 10:29 AM
This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists: Mary Branko and Fred Ramsdell from the United States, and Shimon Sagaguchi from Japan. They have been recognised for their groundbreaking research on peripheral immune tolerance.
Peripheral immune tolerance is a crucial process in the immune system that prevents unwanted or excessive immune responses against the body’s own components (self-antigens) and harmless foreign substances, such as certain food components or beneficial intestinal bacteria. This mechanism ensures that the immune system can defend against harmful pathogens without attacking the body itself or harmless agents.
The official announcement of this year’s Nobel laureates in medicine was made by the Karolinska Institute in Stockholm, Sweden, on Monday at 3:30 PM Bangladesh time.
Prize Details
| Laureates | Country | Research Contribution |
| Mary Branko | United States | Peripheral immune tolerance |
| Fred Ramsdell | United States | Peripheral immune tolerance |
| Shimon Sagaguchi | Japan | Peripheral immune tolerance |
Each laureate will receive:
Nobel Prize Administration
This recognition honours the scientists’ significant contributions to understanding immune system regulation, with potential implications for autoimmune disease treatment, organ transplantation, and immunotherapy.
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